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The Drug Metabolism & Pharmacokinetics (DMPK) department is dedicated to enabling the discovery, development and commercialization of safe and effective medicines by elucidating the mechanisms of absorption, distribution, metabolism, and excretion of synthetic molecule drug candidates. Bioanalysis, as one of the major functional groups in DMPK, is responsible for quantitatively measuring drug molecules in  pre-clinical and clinical studies throughout drug discovery and development, and works in close partnership with various departments outside of DMPK.

The Opportunity

The candidate for the System Specialist Ⅱ position will be involved in the following activities as part of their role:

Identifies, evaluates, implements and optimizes automated systems and process technologies to increase data generating/reporting quality and efficiency

Strong domain knowledge of bioanalytical science, independently perform bioanalytical laboratory assay development and transfer on automated systems (Hamilton liquid handling systems)

Proactively works with users in the maintenance and trouble-shooting of various robotic equipment and systems

Provides guidance to new users on design and transfer of assays to automated systems

Participates in cross-functional teams as a bioanalytical representative to evaluate/implement new automated or data management systems

Work closely with vendors while maintaining a strong focus on efficiency improvements

May participate in bioanalytical support for various drug discovery projects

Who You Are

B.A/B.S (5+ years relevant experience) or MS (3+ years relevant experience) in Chemistry, Biochemistry or engineering disciplines or equivalent experience

Experience with a proven record in automation, programming, data management, and /or process management

Experience operating, programming, and integrating automation instrumentation and peripherals including but not limited to liquid handling platforms (e.g. Hamilton Vantage, Hamilton Star)

Ability to work independently to prioritize effectively and work collaboratively

Strong written and verbal communication skills to document assay implementation, trouble-shooting and internal/external presentations

Preferred

Understanding of bioanalysis and designing high throughput plate-based assays

Biological sample extraction for synthetic molecules using various types of extraction methods

LC-MS/MS quantitative analysis of synthetic molecules

Knowledge programming languages such as Python/C# is a plus

Experience with integrating accessory labware like centrifuges to Hamilton systems is a plus

Relocation benefits are available for this posting.

The expected salary range for this position based on the primary location of California is $91,900 to $170,700.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.