Sr. Downstream Processing Technician
Actalent
Chemistry Lab Tech Job Description
The candidate will help the performance of operations in support of the manufacture of Commercial and Clinical Biologics. They will follow Current Good Manufacturing Practices (cGMPs) and carry out a variety of functions related to Downstream (purification and filtration/HPLC). These functions may include, but are not limited to, activities such as the propagation of mammalian cell culture, conducting aseptic cell culture operations, execution of large-scale production bioreactors (50L - 2000L), and conducting large-scale filtration or centrifugation. Purification will be handled through large-scale chromatography (column and HPLC). The candidate will manufacture buffers and simple bulk reagents per manufacturing procedures with limited supervision and participate in process improvement projects.
Responsibilities
+ Review all area documents.
+ Responsible for the WNS.
+ Assist in the manufacture of controls and calibrators and complete batch records following cGMPs.
+ Perform in-process assays using equipment such as spectrophotometers, pH meters, and clinical analyzers.
+ Weigh, transfer, and mix chemicals as required.
+ Perform product filtrations.
+ Clean and steam steel tanks (CIP/SIP).
+ Prepare glassware and steel tanks for sterilization in autoclave and operate autoclave.
+ Maintain lab equipment including pumps, pH meters, and flow meters.
+ Keep department lead or manager updated on all issues.
+ Monitor stocks of common lab supplies.
+ Perform other job duties as required.
+ Respond to emergency notifications.
+ Work flexible hours and on weekends.
Essential Skills
+ Minimum of 2 years of work experience in manufacturing, operation, production, lab setting or related field.
+ Knowledge of cGMP practices.
+ Aseptic techniques.
+ Chemical concepts.
Additional Skills & Qualifications
+ 6 months of experience in a GMP regulated environment and aseptic technique (preferred).
+ Bachelor's Degree in Science with experience in aseptic technique, chemistry, HPLC, pharmaceutical industry, and bioreactor (preferred).
+ Experience in a cGMP environment and a 4-year STEM degree (preferred).
Pay and Benefits
The pay range for this position is $27.00 - $31.00/hr.
Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: • Medical, dental & vision• Critical Illness, Accident, and Hospital• 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available• Life Insurance (Voluntary Life & AD&D for the employee and dependents)• Short and long-term disability• Health Spending Account (HSA)• Transportation benefits• Employee Assistance Program• Time Off/Leave (PTO, Vacation or Sick Leave)
Workplace Type
This is a fully onsite position in Saint Louis,MO.
Application Deadline
This position is anticipated to close on Apr 22, 2025.
About Actalent
Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.
Diversity, Equity & Inclusion
At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I are embedded into our culture through:
+ Hiring diverse talent
+ Maintaining an inclusive environment through persistent self-reflection
+ Building a culture of care, engagement, and recognition with clear outcomes
+ Ensuring growth opportunities for our people
The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.
If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com (%20actalentaccommodation@actalentservices.com) for other accommodation options.
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