At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. 

Organizational Overview: 

The Bioproduct Research and Development (BR&D) organization develops new medicines that address significant unmet needs by leveraging innovative scientific capabilities. BR&D is a multidisciplinary group with deep technical expertise that works collaboratively with our discovery and manufacturing colleagues. Located in Indianapolis, IN, scientists have full access to Lilly’s deep pharmaceutical development expertise and engineering capabilities. We are looking for a motivated scientist with expertise in analytical chemistry and mass spectrometry to join our Structural Characterization team. The candidate will be part of a highly collaborative, multi-disciplinary team contributing to the development of new therapeutics of various modalities. The ideal candidate will have background and experience on liquid chromatography, mass spectrometry, protein chemistry and spectroscopy techniques, strong problem-solving ability, and the ability to work with cross-functional teams. 

Responsibilities: 

The primary responsibility of this role is to apply cutting-edge mass spectrometry techniques to characterize various therapeutic modalities, such as antibodies, antibody-drug conjugates, antibody-oligonucleotide conjugates, peptides, oligonucleotides, co-formulation products and gene and cell therapies. The candidate will join a state-of-the-art structural characterization group where they will apply broad scientific knowledge and laboratory skills to provide LC-MS support for drug development activities at all stages and across the diverse platform pipeline. 

Key Objectives/Deliverables: 

Independently plan and execute protein characterization tests using LC-MS and ensure timely delivery of characterization data. 

Document data in laboratory notebook, author/review technical reports and contribute to regulatory filings. 

Present data to characterization team, project team, and other co-workers. 

Maintain and trouble-shoot laboratory instruments. 

Evaluate, develop, and implement new characterization techniques and instrumentation. 

Engage with scientists across Eli Lilly’s Discovery, Development and Manufacturing organizations to tackle problems using protein characterization techniques. 

Basic Qualifications 

B.S. in Chemistry or Biochemistry with 3+ years of relevant experience OR M.S. in Analytical Chemistry, Biochemistry, or Chemistry. 

Additional Skills/Preferences 

Understanding of modern MS structural characterization techniques and methodology.   

Hands-on experience with mass spectrometry (e.g., Q-TOF, Orbitrap), chromatographic separations, protein characterization, and/or spectroscopy techniques. 

Experience with maintenance and troubleshooting of liquid chromatography and mass spectrometry instruments. 

Experience with LC-MS data analysis platforms (e.g., BioPharma Finder, Protein Metrics, MassLynx, XCalibur) is a plus. 

Experience with automated liquid handling (e.g., TECAN) for sample preparation is a plus. 

Ability to plan, prioritize and execute multiple activities. 

Strong communication (oral, written), organizational, interpersonal, and leadership skills. 

Ability to work both independently and in an interdisciplinary team environment.  

Good documentation practice. 

Additional Information 

The exact level of the position can range will be commensurate with the candidate’s level of experience. 

Potential exposure to chemicals, allergens, and loud noises. 

Travel: 0 to 15% 

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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