Use Your Power for Purpose

At Pfizer, our purpose is to deliver breakthroughs that change patients’ lives.  As a Senior Associate Scientist, you will be at the forefront of our mission, contributing to the development of innovative therapies that have the potential to transform patient care. We are seeking a highly capable Biochemist or Chemist to assist in automated bioconjugation and characterization of antibody-drug conjugates (ADCs) as part of the core conjugation group within Discovery Research. This person will play a critical role in supporting preclinical efforts to develop novel antibody-based therapeutics.

What You Will Achieve

In this role, you will:

Perform daily operation of Tecan and other automated liquid handlers for high-throughput conjugation of ADCs and sample analysis.Synthesize novel Antibody Drug Conjugates (ADCs), including purification and characterization of ADCs using established and experimental methodologies.Conduct analytical characterization of antibodies and ADCs including HPLC, LC/MS and spectroscopyCollaborate on project teams, present data and demonstrate strong communication skills.Data and report generation including regular review of data with manager, project leads and other research associates.Evaluate new technologies and/or lab efficienciesPrepare critical reagents and maintain inventoriesPerform routine laboratory cleaning and equipment maintenance

Here Is What You Need (Minimum Requirements)

Bachelor's degree with 3+ years relevant experience or M.S. degree with relevant experience; or equivalent.Degree in relevant scientific discipline such as biochemistry, chemistry or related fieldMinimum of 2 years post-baccalaureate lab experience in an academic or industry environment.Experience operating automated liquid handlersExperience performing protein purification and liquid chromatography techniquesDetail-oriented with strong analytical, organizational and multi-tasking skillsAbility to perform routine tasks independently and commitment to high quality analysis and documentationWillingness to work with potent cytotoxic compounds, following safety protocols

Bonus Points If You Have (Preferred Requirements)

Hands-on experience performing analytical HPLC chromatography of proteins and UV spectroscopyAnalytical LC/MS experienceAn ideal candidate will have previous experience performing bioconjugation techniquesKnowledge of protein stability and formulationPrior experience working with electronic lab notebooks and/or LIMS systemsAbility to work collaboratively in a team environmentExcellent organizational and time management skills

  
 

PHYSICAL/MENTAL REQUIREMENTS

Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis.

Additional Information:

Work Location Assignment: On PremiseLast Day to Apply: April 29, 2025

The annual base salary for this position ranges from $66,500.00 to $110,900.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.  This position requires permanent work authorization in the United States.

Research and Development