Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn. Job Description Background of Research and Early Development group: Research and Early Development (RED) is part of the Biologics Analytical Research & Development organization. RED is a protein characterization group focused on mass spectrometry (MS) and analytical innovation. RED works globally with AbbVie’s Discovery and Development Sciences teams to support the biologics screening funnel from lead optimization to candidate selection. AbbVie Biologics Analytical Research & Development is a global analytical sciences organization responsible for all CMC analytical activities related to the development of AbbVie's pharmaceutical products. Our scope includes AbbVie's diverse pipeline of innovative therapeutic biologic medicines and spans from the selection of Discovery candidate molecules through the transition of analytical methods and testing to commercial labs to support product launch. We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make substantial contributions to advance AbbVie's pipeline of innovative medicines! Careers in AbbVie Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies. We are looking for diverse candidates with strong scientific and leadership experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates. This is an excellent opportunity for an experienced scientist with a strong background in mass spectrometry and deeper understanding of protein aggregation mechanism. Your Responsibilities: + Characterization of monoclonal antibodies, Antibody-Drug-Conjugates, novel multi-specifics, fusion proteins, and gene therapies. + Employ modern LC-MS instruments and techniques to understand degradation pathways and gain insight into therapeutic biologic molecules and assess their quality. + Compilation and assessment of analytical data (e.g. mass spectrometry) regarding function and stability of the molecule to support candidate screening in high throughput. Elucidation of structure and impurity/variant characterization of antibody-based drug materials. + Ability to build and manage strategic alignments with key stakeholders, revise and improve business workflows, manage project timelines and resources. Develops the optimal CMC development path for assigned discovery projects together with clients from various discovery and development functions with an emphasis on collaboration, quality and with a sense of urgency. + Operates in a matrix team environment, aligning across and executing shared departmental and divisional strategies. Additionally, the candidate has communication skills, confidence and experience to influence strategic outcomes with stakeholders and matrix teams as needed. + Data review, documentation and preparation of technical memos and reports. Mentor junior staff on troubleshooting equipment and experimental problems + Provision of scientific expertise and engagement in cross-functional teams within AbbVie. Takes initiative to develop independent research ideas and pursues scientific questions that may arise during candidate selection/ nomination screening studies. Presents data at internal and external professional conferences and prepares manuscripts for publication in peer reviewed journals or patent applications. Qualifications Qualifications + BS or equivalent education with typically 7 or more years of experience or MS or equivalent education with typically 5 or more years of experience. + At least 2 years of experience in comprehensive characterization of monoclonal antibodies in an industry setting are beneficial + Experience with characterization of genetic medicines, including AAVs and LNPs, is highly desired + Deep understanding of protein characterization by LC/ESI-HR-MS (e.g. peptide Mapping, intact mass analysis) and insights into the causes of protein degradation + Knowledge of functional excipient degradation pathways is a plus + Experience in determination of PTM and chemical modifications and their influence on the molecule’s function and structure + Additional robotics expertise and protein analytical experience (e.g. SEC, IEX, HIC, CE) is beneficial + Highly motivated, self-driven and results-oriented person with excellent communication and presentation skills + High degree of flexibility in adapting to different projects and people; embraces the ideas of others, nurtures innovation and manages innovation to reality + Excellent team player with the ability to build strong networks with peers Key AbbVie Competencies: + Builds strong relationships with peers and cross functionally with partners outside of teams to enable higher performance. + Learns fast, grasps the "essence" and can change course quickly where indicated. + Raises the bar and is never satisfied with the status quo. + Creates a learning environment, open to suggestions and experimentation for improvement. + Embraces the ideas of others, nurtures innovation and manages innovation to reality. Level and compensation will be commensurate with experience. An equal opportunity employer. AbbVie welcomes and encourages diversity in our workforce. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​ ​ + The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​ + We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​ + This job is eligible to participate in our short-term incentive programs. ​ ​ Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​ ​ ​ ​ AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html Salary: $91,500 - $173,500