**Work Schedule** First Shift (Days) **Environmental Conditions** Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Cold Room/Freezers -22degreesF/-6degrees C, Laboratory Setting, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Will work with hazardous/toxic materials **Job Description** **Job Title: Scientist II, Protein Purification** Join the Thermo Fisher Scientific team to make a global impact through meaningful work. Help us enable customers to create a healthier, cleaner, and safer world. Develop solutions for challenging issues like environmental protection, food safety, and cancer research. **Discover Impactful Work:** You will join a team performing all tasks related to protein purification. You will work in a controlled manufacturing facility under controlled conditions using purification equipment and analytical techniques. **A Day in the Life:** + Purification of protein products in a lab setting by applying standard operating procedures. Use basic laboratory techniques, calculations, and materials measurement. Operate laboratory equipment and maintain accurate records in order to ensure controlled product manufacturing. + Perform column purification/chromatography, tangential flow filtration (TFF), buffer preparation, SDS-Page Analysis, Western Blotting, and other protein characterization techniques. + Responsible for Batch Data Records, notebooks (if required) and work order documents. + Apply technical knowledge and skills to make detailed observations and analyze data to ensure it falls within operating parameters. Notifies the manager about any factors that may impact the product's quality. + Maintain equipment, product inventories and related records as assigned. + Complete, distribute and file records as required in accordance with Document Control Practices under controlled conditions. + Align with all company safety regulations and procedures and report any instances of non-compliance. + Maintain knowledge of SDSs for relevant products/materials. + Operate a safe work environment through continuous safety awareness and full compliance to all EH&S programs and activities. + Identify potential issues in a process; report findings to team management, perform troubleshooting (as required) and identify solutions. + Modify technical documents which include standard operating procedures and manufacturing batch records within the requirements of the quality management system. + Supports process improvement projects (as required) to reduce process scrap or improve quality and productivity. + May perform other related duties as required and/or assigned. **Experience:** + Bachelor’s degree in biological science preferred and 2+ years’ experience in the application of cellular or microbiology laboratory techniques in a manufacturing environment or R&D laboratory (or equivalent combination of education and experience). + Intermediate knowledge and experience with protein biochemistry and chromatography techniques. + Strong understanding of GLP and GMP processes and documentation. + Demonstrated experience on AKTA or NGC Purifier Systems. + Excellent communication (written and oral) skills, and the ability to work in a multidisciplinary team environment. Highly motivated and dedicated individual who is well organized, meticulous with strong social skills and the ability to multitask. **Knowledge, Skills, Abilities:** + Consistent, diligent and accurate in carrying out responsibilities. + Displays positive attitude toward job and others. + Follows and provides direction accurately and efficiently. + Excellent documentation and communication skills. + Results oriented and data driven. + Demonstrated ability to carry out scientific procedures and make documented improvements. + Demonstrated problem-solving skills using quality and lean tools. + Experience with different modes of chromatography such as: affinity, ion-exchange, size exclusion, hydrophobic interaction. Understanding of protein/resin interactions. + Applies lean tools to ensure processes are carried out right the first time. + Theoretical understanding of protein chemistry, methods and techniques. + Proactive approach that anticipates needs and problems while creating solutions. + Strong collaborative skills and the ability to influence others without authority. + Working knowledge of manufacturing related computer software preferred. + Intermediate Excel skills. **Working Conditions:** + Works in a clean, controlled, manufacturing lab environment with specialized equipment. + Regularly required to lift up to 20 pounds. May lift weight of 45 pounds or more, with assistance and/or with equipment on occasion. + May be required to stand for long periods of time while performing duties. + Must be flexible to work varying schedules and hours as needed. + Must work safely with chemicals and hazardous materials. + Must work in +4ºC Cold-Room. **This position does not offer relocation benefits.** **Benefits:** Our company provides a comprehensive benefits package including competitive compensation, annual incentives, healthcare coverage, and various employee benefits. Thermo Fisher Scientific presents an opportunity to work for a forward-thinking organization with excellent career growth and development opportunities. Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other legally protected status. We will gladly provide reasonable accommodations covered under the ADA. **Compensation and Benefits** The hourly pay range estimated for this position based in California is $31.73–$47.60. This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes: + A choice of national medical and dental plans, and a national vision plan, including health incentive programs + Employee assistance and family support programs, including commuter benefits and tuition reimbursement + At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy + Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan + Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.