This is an onsite position based in Cambridge, UK
Job advert closing date: February 7, 2025
Illumina's employee benefits are industry-leading and include, flexible time off, private medical insurance, compassion and care time off, leisure travel insurance, pension, employee stock purchasing program, volunteer time off, and much more!
The Role
As Scientist-1 in the Reagent Science division, you will join a highly multi-disciplinary team that works at a fast pace to create robust and innovative products for the Next Generation Sequencing (NGS) platforms offered by Illumina. You will deploy a variety of analytical methodologies, biochemical and biophysical assays to drive the progress of the latest ILMN technology. You are going to focus on the characterization of novel enzymes and formulations that will be commercialized as reagents for the next Illumina sequencing chemistry.
Together with you team members, you will share the responsibility of developing stable and robust enzyme-dependent reagents and you will learn how to perform on-sequencer optimization of those reagents. And our team of talented scientists will be there to support this journey into R&D methods and platforms, helping you to develop the necessary skills to progress your career.
Key Responsibilities:
Optimization and execution of biochemistry, biophysics and molecular biology lab-based experimentation to characterize new and existing reagents, enzymes, and processes to achieve commercial levels of stability, robustness, and performanceOperation of state-of-the-art equipment including plate readers, Illumina sequencers and liquid handling roboticsCommunication and presentation of results to local and global project teamsHighly accurate recording and documentation of procedures and resultsManage goals within defined timelinePerform data analysis and interpretation of large data setsTroubleshoot instrumentation issuesEffective collaboration with other scientists including bioinformaticians, chemists and protein engineersListed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.
Preferred Background, Skills And Experience
A Bachelor’s/Advanced degree in Biochemistry, Biotechnology, Biophysics, Protein Chemistry, Molecular Biology or a related field1+ years laboratory experience in academia, a research institute, a biotech company or a drug discovery company desirableStrong team-player attitudeGood communication, record keeping and presentation skillsGood understanding of statistical significance, replicates, controlsThe capability to be flexible in a fast-paced and dynamic environmentThe ideal candidate should have experience with at least one of the following techniques: polymerase activity assays, kinase activity assays, Fluorescence Polarisation/Anisotropy assays, FRET, HPLC of proteins/peptides/oligonucleotides, protein Size Exclusion Chromatography, SPR, BLI Octet, DLS, EMSA, Calorimetry (ITC, DSC), AlphaScreen Assays.Experience with one or more of the following approaches will be an advantage but is not essential: plate readers, automated pipetting robots, Next Generation Sequencing, characterisation of DNA binding proteins, single molecule spectroscopy, characterisation of fast kinetics (Stop-Flow or Quench-Flow),X-Ray Crystallography of proteins, Electron Microscopy, SEC-MALS, JMP-SAS softwareWhat can you expect
Our team members are bright, energetic and dedicated - they are the driving force behind our innovation and impact. To attract the best and brightest, we offer a competitive employee benefits program. We view it as a smart investment in our people, one that recognizes the tremendous value they bring to our business every day. At Illumina, we push boundaries. We think beyond the conventional. We dream big. With the energy of so many bright and accomplished people, the opportunities are endless.
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Illumina believes that everyone has the ability to make an impact, and we are proud to be an equal opportunities employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.