Research Associate II
Actalent
Job Title: Research Associate IIJob Description
We are seeking a highly motivated and enthusiastic Research Associate II to join the Seattle Pilot Facility (SPF) within the oncology Process Development group. This role will primarily support Downstream cell culture operations in our pilot-scale lab (up to 250L) to generate protein materials needed for cross-functional developments and GLP toxicology studies. The successful candidate will independently execute purification processes from harvest to final fill and be cross-trained in Upstream cell culture processes. This is an exciting opportunity to learn the entire monoclonal antibody (mAb) production process, join a dynamic team, and significantly contribute to our mission.
Responsibilities
+ Support protein material generation activities, including both purification and mammalian cell culture operations, from cell thaw to final formulated mAb.
+ Escalate equipment or process issues as necessary. Assist in troubleshooting and derivation of appropriate corrective actions and resolutions.
+ Prepare buffer and media solutions to support material generation and process development runs.
+ Perform maintenance on equipment such as bioreactors, purification skids, pH meters, and chromatography columns.
+ Maintain accurate and detailed records of all lab activities and work routinely with electronic data records and applications.
+ Generate technical reports and present them in internal meetings.
+ Order and manage raw materials and consumables.
Essential Skills
+ Hands-on experience in purification processes and operations, preferably at pilot or manufacturing scales.
+ Ability to follow lab operating procedures and safety guidelines.
+ Detail-oriented with strong organizational and time management skills.
+ Team player with motivation and willingness to learn and grow.
+ Effective written and verbal communication skills.
+ Familiarity with lab software and/or electronic lab notebooks (ELN).
+ Ability to lift and move 50 lbs. repeatedly.
+ Willingness to work weekends and holidays when needed.
Additional Skills & Qualifications
+ Familiarity with cell culture experience, including operating both bench-top glass vessels and large-scale single-use bioreactor systems.
+ Proficiency in lab automation.
+ Proficiency with ELN and data management.
Work Environment
The work environment includes a pilot-scale lab equipped with bioreactors, purification skids, pH meters, and chromatography columns. The role requires maintaining accurate records using electronic lab notebooks and managing raw materials and consumables. The position may involve lifting and moving 50 lbs. repeatedly and requires flexibility to work weekends and holidays when necessary.
About Actalent
Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.
Diversity, Equity & Inclusion
At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I are embedded into our culture through:
+ Hiring diverse talent
+ Maintaining an inclusive environment through persistent self-reflection
+ Building a culture of care, engagement, and recognition with clear outcomes
+ Ensuring growth opportunities for our people
The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.
If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com (%20actalentaccommodation@actalentservices.com) for other accommodation options.
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