Framingham, MA, USA
3 days ago
Principal Research Associate Purification Process Development

About the Job

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Purification Process Development (part of Sanofi R&D and Global CMC Development) is responsible for development, scale-up, transfer, and characterization of purification processes for clinical and commercial manufacturing of therapeutic proteins from the mammalian production platform. In addition, the department develops next-generation bioprocessing and process development technologies such as integrated and continuous bioprocessing, high throughput process development, and mechanistic modeling of bioprocesses. The department also works to support a global purification network and update our purification platform.

The Principal Research Associate will join a dynamic and motivated team to develop downstream purification processes in support of early and late-stage drug development programs. In addition, the Principal Research Associate will support the tech transfer of the developed processes, while ensuring the highest standards of safety, environmental, and regulatory compliance are maintained in the workplace.

Independently plan and execute process and technology development experiments using high throughput purification models and benchtop and/or pilot scale chromatography and filtration systems

Develop areas of specific technical expertise and apply knowledge across projects

Develop novel hypotheses to solve complex technical problems and meet project team objectives

Represent department in cross-functional interactions

Prepare internal technical reports and present project outcomes and/or technology advancements internally; may present externally at industry conferences

About You

Earned Masters degree in Chemical Engineering, Biochemical Engineering, Biochemistry or related field with 2 years of relevant experience, or Bachelor's degree with 4 or more years of relevant experience

Relevant laboratory experience, in either an academic or industrial setting is preferred

An understanding of scientific principles underlying purification technologies and operations

Experience with statistical analysis and modeling

Excellent planning, organization, and written and oral communication skills

High level of scientific curiosity

Logical and critical thinking skills, innovative problem-solving

Ability to work independently and also in a collaborative team environment


At Sanofi R&D North America, we deliver meaningful solutions for patients. We transform science into breakthrough, best-in-class and first-in-class medicines and vaccines. We believe in creating a diverse and inclusive workforce – and workplace – which brings together the collective brainpower of over 2,000 colleagues and provides you with an exciting place to grow and develop. We set the bar high, and we deliver. Join us and together we will build on our trusted legacy of breakthroughs for society.

Why Choose Us?

Bring the miracles of science to life alongside a supportive, future-focused team.

Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SA 
#LI-SA
#LI-Onsite 

Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

Confirm your E-mail: Send Email