McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

Job Title : MTAP - Lead Security Architect – Microsoft 365 Focus

Position Overview:

The Lead Security Architect at the P5 level is a senior role specializing in designing, implementing, and maintaining security solutions within the Microsoft 365 ecosystem. This position focuses on safeguarding email, collaboration tools, and other M365 features while ensuring the organization fully leverages the platform's capabilities. The role requires deep expertise in Microsoft 365 security features, an understanding of emerging threats, and a strategic vision for protecting the organization's digital workspace.

As a key technical leader, the Lead Security Architect collaborates with stakeholders to develop and implement best practices, ensuring alignment with regulatory requirements and organizational objectives.

Key Responsibilities

Microsoft 365 Security Architecture

Design and implement robust security architectures for Microsoft 365 environments, focusing on email, collaboration tools (e.g., Teams, SharePoint, OneDrive), and other platform features.Develop security blueprints, design specifications, and architectural diagrams tailored to M365.Identify and mitigate vulnerabilities within the M365 ecosystem, ensuring resilience against modern cyber threats.

Email Security and Threat Protection

Lead the deployment and optimization of Microsoft Defender for Office 365, focusing on email security, anti-phishing, and anti-malware protections.Implement advanced threat protection measures, including safe links, safe attachments, and real-time threat intelligence.Develop strategies to combat Business Email Compromise (BEC), ransomware, and other email-based threats.

Collaboration Security

Ensure the secure configuration of Teams, SharePoint, and OneDrive for Business, with a focus on data governance and access control.Implement Data Loss Prevention (DLP) policies, Conditional Access, and Rights Management to secure shared files and collaboration workflows.Optimize user and group policies to balance security with productivity.

Identity and Access Management (IAM)

Leverage Azure AD for secure identity management, including Multi-Factor Authentication (MFA), Privileged Identity Management (PIM), and conditional access policies.Design and enforce Zero Trust principles across the Microsoft 365 platform.Monitor and manage secure external sharing and guest access configurations.

Monitoring, Threat Detection, and Incident Response

Implement and optimize Microsoft Sentinel for real-time monitoring, threat detection, and correlation of M365 logs.Develop automated incident response workflows using Microsoft tools like Power Automate and Defender for Cloud Apps.Provide expertise during security incidents, focusing on root cause analysis and mitigation strategies specific to M365 environments.

Compliance and Data Governance

Ensure compliance with relevant frameworks such as GDPR, HIPAA, and ISO 27001 through the proper use of M365 Compliance Center features.Configure and monitor information protection policies, including sensitivity labels, retention policies, and eDiscovery solutions.Support audit readiness and documentation for Microsoft 365 security configurations.

Collaboration and Communication

Act as the primary liaison between technical teams, business units, and leadership for M365 security matters.Present complex security concepts related to Microsoft 365 to diverse audiences, including senior executives and non-technical stakeholders.Drive cross-functional initiatives to embed Microsoft 365 security best practices into operational processes.

Innovation and Continuous Improvement

Stay informed about emerging Microsoft 365 features and their security implications.Proactively identify opportunities to enhance the organization’s M365 security posture through new tools, policies, or configurations.Champion long-term projects to improve the adoption and secure use of M365 platform capabilities.

Required Qualifications

Education

Bachelor’s degree in Computer Science, Information Technology, Cybersecurity, or a related field.

Experience Required:

8–10 years of professional experience in cybersecurity, with significant focus on Microsoft 365 security.Proven track record of designing and securing enterprise-scale M365 deployments.Experience in managing email, collaboration, and data protection security within Microsoft environments.

Must have technical skills:

Expertise in Microsoft 365 security tools such as Microsoft Defender for Office 365, Compliance Center, Azure AD, and Microsoft Sentinel.Strong knowledge of email security, collaboration tools, and IAM principles.Proficiency in configuring and managing DLP policies, conditional access, and information protection features.Familiarity with PowerShell scripting for M365 administration and automation.

Certifications

Relevant certifications such as Microsoft Certified: Security, Compliance, and Identity Fundamentals; Microsoft 365 Certified: Security Administrator Associate; or equivalent certifications (CISSP, CISM, etc.).

Soft Skills

Strong analytical and problem-solving skills, with a proactive mindset for addressing M365 security challenges.Ability to influence and guide technical teams and business stakeholders.Excellent verbal and written communication skills, with the ability to present technical concepts clearly and effectively.

Physical Requirements: General Office Demands

 

Candidate must be authorized to work in the U.S, now or in the future, without the support from McKesson.

 

Relocation is NOT budgeted for this position.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$139,000 - $231,600

McKesson is an Equal Opportunity Employer

 

McKesson provides equal employment opportunities to applicants and employees and is committed to a diverse and inclusive environment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age or genetic information. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

 

Join us at McKesson!