Life Science Research Professional 2 **School of Medicine, Stanford, California, United States** Research Post Date Oct 29, 2024 Requisition # 105058 **Life Science Research Professional 2 – Xiao Lab** The Xiao Laboratory is a part of the Stanford Biochemistry and Stanford Cancer Institute (SCI). We are a chemical systems biology group focused on developing creative mass spectrometry (MS)-based strategies, combined with data science, to understand mechanisms of metabolic regulation over protein function in health and disease. We aim to use this as a basis to develop translational therapeutics for aging, metabolic disease, and cancer. SCI is one of an elite number of National Cancer Institute-Designated Comprehensive Cancer Centers in the country, and is a prominent, dynamic, growing and complex Institute within the Stanford University School of Medicine. The SCI actively works to build synergies and collaborations among faculty with cancer-relevant expertise from four Schools and over 30 departments across Stanford University. Given the SCI’s mission, breadth, and depth, it employs over 325 staff members in a fast-paced, team-oriented, and forward-thinking environment with tremendous opportunities for personal and professional growth. You will be working with an unparalleled leading-edge community of faculty and staff who work on both basic science and clinical/translational investigations, and who are fundamentally changing the world of biomedical science and health care. We are seeking a Life Science Research Professional 2 to perform experiments and data analysis, to contribute to publications, and to support activities in a newly-established group at Stanford. The successful candidate will perform cellular and animal experiments, proteomics, metabolomics, and computational analyses that interface with ongoing biology efforts in the laboratory. The role is highly collaborative with opportunities for independent work that contributes to long-term goal of the laboratory. The LSRP2 will perform complex functions and activities involved in defined research projects, and independently conduct a portion of the research project(s). The LSRP2 will be able to directly work with the principal investigator and other members of the lab in a collaborative environment. The candidate will be conversant in the goals, mission and priorities of the Institute. We are seeking candidates with excellent organizational and communication skills. Our staff embrace challenges with a high degree of professionalism, initiative and flexibility. **Duties include*:** + Independently conduct a portion of the research project(s). Make recommendations on experimental design and/or research direction to principal investigator. + Independently conduct complex (lab and/or field) experiments to gather data for a portion of a major research project. + Interpret and analyze results, often where few guidelines exist, and make modifications to existing procedures and protocols. + Develop new research protocols where appropriate protocols are not described in the literature or where modification or adaptation of standard procedures and protocols is required. + Participate in multidisciplinary teams across different faculties or schools. + Perform ongoing literature review to remain current with new procedures and related research; apply to ongoing research and development of new protocols. + Contribute substantively to the preparation of papers for publication, especially in the results section, and to publication of findings. Present ongoing work to colleagues and/or academic conferences. + Oversee supply and equipment budget under supervision of principal investigator or business manager. + Work with health and safety department to ensure lab complies with regulations and all required trainings. + Supervise (either formally or informally) staff or students as needed, including oversight and direction on techniques, as well as consultation on project work. Serve as a technical resource for other research staff. + Oversee the daily activities of the laboratory including lab maintenance; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed. May assist with purchasing laboratory equipment. _*- Other duties may also be assigned._ **DESIRED QUALIFICATIONS:** The desired candidate should have expertise in the following areas: + Outstanding mammalian cell culture techniques. + Expertise in basic cellular and molecular biology techniques including, but not limited to, PCR, protein/DNA/RNA extraction and gel electrophoresis, bacterial transformation, imaging, cloning, gene-editing (such as CRISPR), small and large scale plasmid purification, sequencing, transfection by electroporation, transduction of viral supernatants into cell lines, and using standard software (such as Image J, BioRad, SnapGene, etc) to facilitate biological experiments. + Experience working with mice and performing animal physiology experiments. + Expertise in these following areas below is a big plus: + Expertise in the field of cancer metabolism. + Expertise in mass spectrometry-based proteomics and metabolomics. + Expertise in using R/python or similar software to perform bioinformatic analysis, such as GO analysis, network analysis, and machine learning. + A bachelor’s degree in biological sciences or related fields is required. Candidates with strong research experience and a computational background are encouraged to apply. **EDUCATION & EXPERIENCE (REQUIRED):** Bachelor's degree in related scientific field and two years of relevant work experience; or Master’s degree in a related scientific field. **KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):** + Comprehensive understanding of scientific principles. + General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications. + Strong analytical skills and excellent judgment. + Ability to maintain detailed records of experiments and outcomes. + Ability to work under deadlines with general guidance is essential. + Excellent organizational skills and demonstrated ability to accurately complete detailed work. **PHYSICAL REQUIREMENTS*:** + Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds. + Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts. + Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls. + Must have correctible vision to perform duties of the job. + Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours. + Ability to lift heavy objects weighing up to 50 pounds. + Ability to work in a dusty, dirty, and odorous environment. + Position may require repetitive motion. _*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job._ **WORKING CONDITIONS:** + May require working in close proximity to blood borne pathogens. + May require work in an environment where animals are used for teaching and research. + Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present. + Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator. + May require extended or unusual work hours based on research requirements and business needs. **WORK STANDARDS:** + Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations. + Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors bases on training and lessons learned. + Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University’s Administrative Guide,http://adminguide.stanford.edu. _The expected pay range for this position is $81,130 to $94,895 per annum._ _Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and_ _external market pay for comparable jobs._ _At Stanford University, base pay represents only one aspect of the comprehensive rewards package. The Cardinal at Work website (https://cardinalatwork.stanford.edu/benefits-rewards) provides detailed information on Stanford’s extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process._ _Consistent with its obligations under the law, the University will provide reasonable accommodations to applicants and employees with disabilities. Applicants requiring a reasonable accommodation for any part of the application or hiring process should contact Stanford University Human Resources by submitting acontact form._ _Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law._ _The job duties listed are typical examples of work performed by positions in this job classification and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned._ Additional Information + **Schedule: Full-time** + **Job Code: 4952** + **Employee Status: Regular** + **Grade: G** + **Requisition ID: 105058** + **Work Arrangement : On Site**