Site Name: UK - Hertfordshire - Stevenage, USA - Pennsylvania - Upper Providence Posted Date: Feb 7 2025 We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme. We embrace modern work practices; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work. Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK GSK is looking for exceptional, ambitious and experienced group leader for the Spatial Multiplex Imaging team in Non-Clinical Histology, Bioimaging at our R&D site in Upper Providence, US or in Stevenage, UK. This exciting role provides a rare opportunity for the applicant to lead a group of talented scientists based in the UK and in the US focusing on tissue-based spatial biology and associated data analytics to deliver decision-making data for GSK’s portfolio from target validation to late-stage assets. This role will be focused on using cutting edge technologies that bridge imaging and omics domains to enable high-resolution, highly multiplexed localization and quantitation of targeted RNA and protein panels at single cell level or better. This requires a maintenance of expertise and knowledge of new assays and technologies for advanced, multiplexed histological evaluation, from external (e.g. vendors, academic groups) as well as their own bespoke work for project endpoints. In this role you will Utilize expertise in tissue spatial omics technologies (transcriptomics, proteomics, etc), multiplexed imaging, multi-omics integration, and computational/digitally assisted analysis to support GSK programmes and to deliver focused spatial biology transcript/protein/drug measurements to address specific hypotheses around mode/mechanisms of action or spatial localisation of cells/cellular responses that are not possible with bulk tissue or disaggregated cell measurements. Define and drive the scientific strategy of the Spatial Multiplex Imaging team and orchestrate scientific innovation in the field by overseeing all aspects of the facility, managing and developing personnel as appropriate to meet the evolving needs of the company and staying ahead of technological trends including computational technologies. Lead an integrated group of high-performing scientists and manage and oversee the portfolio of projects supported by the group. Provide support to direct reports as needed for assay strategy and design, assay development and optimization, troubleshooting, sample acquisition, data processing, and all aspects of QC ensuring timely delivery of Spatial Multiplex Imaging studies in support of discovery programs. Forge strong partnerships with multidisciplinary teams (including BioImaging, PCS, Research Units, Precision Medicine, HBSM, and Pathology) and with enterprise teams (including Onyx, DaPS, data management, programming, and bioinformatics scientists) to define standards for spatial transcriptomic and proteomic data and to find solutions to expedite the transfer of multi-modality data to key stakeholders. Develop trusted connections in the scientific community (internally and externally to GSK) and support strategic collaborations with academic institutions, and other external partners. Ensure compliance of laboratory staff with data standards and that all activities comply with appropriate Health and Safety legislation, Company Codes of Practise and local rules, and are conducted in a safe manner. Why you? Basic Qualifications & Skills: We are looking for professionals with these required skills to achieve our goals: MSc or PhD with extensive years of post-graduate experience in a relevant scientific discipline ( e.g., immunology, molecular or cellular biology, cancer biology, neurobiology, genomics, biomedical science, experimental pathology or related disciplines). Extensive experience in leading a team and managing projects. Able to show definitive decision making to manage workloads, multiple projects and accurately estimate timelines to meet deadlines. Strong knowledge on Human Tissue Act and experience in histotechnology, including specimen processing and routine histology. Strong knowledge and practical experience in working with spatial-omic platforms (Visium, Xenium, CellDive, Cellscape, etc) including the design, implementation and interpretation of spatial-omics experiments and data. Excellent communication and proactive attitude with the ability to effectively communicate complex scientific concepts to both technical and non-technical audiences in a balanced, clear and precise manner. Ability to maintain a disciplined approach, with a strong attention to detail with a focus on quality, compliance, scientific rigor, and operational excellence. Preferred Qualifications & Skills: Please note the following skills are not necessary, just preferred, if you do not have them, please still apply: A good understanding of the drug development process from previous experience working in a biopharmaceutical environment. Experience in using software applications in image analysis, genomic analysis, data analysis/visualization and data interpretation Established external profile and key opinion leadership, including strong publication track record. Existing network of expert histotechnology leaders throughout academia, industry or government entities Willingness to develop and train others as required Closing Date for Applications – Friday the 21st of February (COB) Please take a copy of the Job Description, as this will not be available post closure of the advert.  When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only). We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. 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