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Job Description

The Early Chemistry, Manufacturing, Controls (CMC) process development group serves as the link between discovery and manufacturing for oncology programs. Our mission is to ensure that emerging projects are scalable, manufacturable, cost-effective, and efficacious for patients. We collaborate closely with the Drug Discovery Units (DDUs) and other CMC teams, bridging the gap between research and manufacturing.

Job Description:

The intern will work on a project to determine nutrient usage, byproduct accumulation, and cytokine uptake in gamma delta T (gdT) cells across large-scale, small manufacturing model, and bioreactor processes.

How You Will Contribute:

Determine how media components are being used by gdT cells throughout manufacture across large-scale, small manufacturing model, and bioreactor processesAssess any differences across the processesCollaborate with Data and Automation teams to determine the impact of optimized nutrient availability and cytokine concentration using data obtained through a design of experiments approach (DoE) using a high-throughput system (HTS)Correlate variables to in-process data and functional readouts with the help of the Data teamAssess top conditions in small manufacturing models

Internship Development Opportunities:

Gain understanding of media composition and its importance to cell health, expansion, and final drug product quality/potencyUnderstand how gdT cells use nutrients and cytokines throughout their expansionUnderstand what the effect of changing nutrient availability during expansion has on final drug product quality/potencyUnderstand the gdT manufacturing processes and the relationship/crosstalk across manufacturing, scalable manufacturing models, and bioreactorsDevelop lab skills and learn process workflows: aseptic technique, cell culture, cell counting; cell isolation, transduction, expansion, harvest, cryopreservationLearn to communicate and work effectively in a cross-functional setting

Job Requirements:

This position will be Fully Onsite and require 4+ days in the Cambridge office per week.Must be pursuing a Master’s or Doctoral Degree in a relevant Field of StudyExperience with cell culture, aseptic technique, and lab safetyBasic understanding of immunologyBasic knowledge of statisticsPrior experience in process development a plusPrior experience with automation a plusPrior experience with bioreactors a plusBasic understanding of computer skills including MS Office (PowerPoint, Words, Excel)Internet skills including use of e-mails, group messaging and information gatheringHighly reliable and a strong team playerFlexible with an attention to detailStrong verbal and written communication skills

Internship Eligibility

Must be authorized to work in the U.S. on a permanent basis without requiring sponsorshipMust be currently enrolled in a degree program graduating December 2025 or laterThe internship program is 10-12 weeks depending on the two start dates (June 2nd- August 22nd) or (June 16th - August 29th)The intern must be able to commit to one of these time framesAble to work full time 40 hours a week during internship datesTakeda does not provide a housing stipend or relocation support for the U.S Summer Internship Program

 Program Highlights:

Hands-on experience with real projects and responsibilitiesDedicated mentorship program pairing interns with experienced professionalsNetworking opportunities with industry professionals and fellow internsInternship events focused on professional and skills developmentExposure to multiple business areas or departments within a Pharmaceutical Organization

Applications will be accepted between January 6th and January 31st

Takeda Compensation and Benefits Summary 

We understand compensation may be an important factor as you consider an internship opportunity. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Hourly Wage Range:

$21.00 - $46.00

The estimated hourly range reflects an anticipated range for this position. The actual hourly wage offered will depend on the candidate’s school year/level to be entered following completion of internship.  The actual hourly wage offered will be in accordance with state or local minimum wage requirements for the job location. 

 

U.S. internship benefits vary by location and may include: 

 Paid sick time 

Civic Duty paid time off 

Participation at company volunteer events  

Participation at company sponsored special events  

Access to on-site fitness center (where available) 

Commuter Benefit: To offset your work-commute expenses, Takeda provides U.S. employees with a fixed monthly subsidy to be used for either public transportation (transit) or parking.  

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypePaid Intern (Fixed Term) (Trainee)

Time TypeFull time

Job Exempt

No