2025 Summer Intern - Translational Pharmacokinetics/Pharmacodynamics

Department Summary

This intern position is in the Translational Pharmacokinetics (PK) & Pharmacodynamics (PD) or tPKPD Department within Development Sciences. The tPKPD department applies preclinical models (in silico, in vitro or in vivo) to determine the pharmacokinetics (what the body does to the drug) and/or pharmacodynamics (what the drug does to the body) of biotherapeutics. The information obtained from such work is often used to help select lead molecules, optimize dosing regimens and understand the PK behavior/metabolic fate of different molecular designs as we help advance molecules through stages of research and into early clinical development.  The work within the tPKPD department spans across a wide range of disease areas, including oncology, immunology, ophthalmology, infectious disease and neuroscience. 

This internship position is located in South San Francisco, on-site.  

The Opportunity

Collaborate with PKPD scientists to analyze bioinformatics data and derive insights into TMDD relationships.

Develop and validate predictive models using publicly available and Roche's internal data sets.

Contribute to the evaluation of target behaviors and druggability assessment in preclinical stages.

Engage with cross-functional teams across the organization to present results and incorporate feedback.

Work on impactful projects with some of the most talented professionals in the biotechnology industry.

This is a unique opportunity to gain hands-on experience in applying bioinformatics to drug development. Apply today and make a meaningful impact on the future of therapeutic innovation at Genentech.

Program Highlights

Intensive 12-weeks, full-time (40 hours per week) paid internship.

Program start dates are in May/June (Summer)

A stipend, based on location, will be provided to help alleviate costs associated with the internship. 

Ownership of challenging and impactful business-critical projects.

Work with some of the most talented people in the biotechnology industry.

Who You Are 

Required Education:  You meet one of the following criteria:

Must be pursuing a Master's Degree (enrolled student).

Must have attained a Master's Degree.

Must be pursuing a PhD (enrolled student).

Preferred Majors: 

Bioinformatics, computational biology, chemical engineering, biomedical engineering, bioengineering, applied mathematics, computer science, or other related pharmaceutical sciences.

Required Skills: 

3+ years of hands-on experience with R, Python, and other bioinformatics analysis tools/software (i.e. Seurat).

Strong interpersonal and oral/written communication skills with high attention to detail.

Applicants must be currently enrolled in an academic program.

Preferred Knowledge, Skills, and Qualifications

Excellent communication, collaboration, and interpersonal skills.

Familiarity with version control is a plus.

Experience with pharmacokinetics and pharmacodynamics principles.

Some experience in MATLAB is a plus

Relocation benefits are not available for this job posting. 

The expected salary for this position based on the primary location of California is $50 hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

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