2025 Summer Intern - Modeling and Simulation, Translational Pharmacokinetics and Pharmacodynamics - Development Sciences
Department Summary
This intern position is in the Translational Pharmacokinetics (PK) & Pharmacodynamic (PD) or tPKPD Department within Development Sciences. The tPKPD department applies preclinical models (in silico, in vitro or in vivo) to determine the pharmacokinetics (what the body does to the drug) and/or pharmacodynamics (what the drug does to the body) of our biotherapeutics. The tools used by tPKPD can be based in a computational setting and/or laboratory setting depending on the questions being asked and hypotheses being tested. The information obtained from this work may be used to help select lead molecules, optimize dosing regimens or understand the PK behavior/metabolic fate of different molecular designs as we help advance molecules through stages of research and into early clinical development. The work within the PTPK department spans across a wide range of disease areas, including oncology, immunology, ophthalmology, and neuroscience.
This internship position is located in South San Francisco, on-site.
The Opportunity
The Modeling and Simulation (M&S) group within tPKPD is seeking a highly motivated graduate student interested in mechanistic modeling. The intern will work with Quantitative Systems Pharmacology (QSP) scientists on modeling of brain distribution of large molecules and oligonucleotides by developing, calibrating, simulating, and analyzing a QSP model to support our neuroscience portfolio. The intern will have the opportunity to influence key stakeholders of potential clinical impacts of these novel therapies. The summer intern is expected to give a formal presentation at the end of the program.
Program Highlights
Intensive 4 months, full- time, with possibility to extend to 6 months.
Program start dates are in May/June 2025.
A stipend, based on location, will be provided to help alleviate costs associated with the internship.
Ownership of challenging and impactful business-critical projects.
Work with some of the most talented people in the biotechnology industry.
Who You Are (Required)
Required Education
Must be pursuing a PhD (enrolled student)
Required majors: Chemical engineering, biomedical engineering, bioengineering, bioinformatics/computational biology, applied mathematics, computer science or other pharmaceutical sciences fields preferred.
Required skills:
3+ years of hands-on experience with Matlab/Simbiology, R, Python, or other ordinary differential equation software.
Strong interpersonal and oral/written communication skills with high attention to detail.
Applicants must be currently enrolled in an academic program.
Preferred Knowledge, Skills, and Qualifications
Familiarity with version control platforms is a plus.
Domain knowledge in neuroscience is also a plus.
Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.
Relocation benefits are not available for this job posting.
The expected salary range for this position based on the primary location of California is $50.00 per hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.
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